Structure-Based Analysis of A19D, a Variant of Transthyretin Involved in Familial Amyloid Cardiomyopathy

Transthyretin (TTR) is a tetrameric beta-sheet-rich protein. Its deposits have been implicated in four different amyloid diseases. Although aggregation of the wild-type sequence is responsible for the senile form of the disease, more than one hundred variants have been described thus far, most of wh...

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Detalles Bibliográficos
Autores principales: Ferreira, Priscila, Sant’Anna, Oliveira, Varejão, Nathalia, Lima, Cinthia, Novis, Shenia, Barbosa, Renata V., Caldeira, Concy M., Rumjanek, Franklin D., Ventura, Salvador, Cruz, Marcia W., Foguel, Debora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866121/
https://www.ncbi.nlm.nih.gov/pubmed/24358189
http://dx.doi.org/10.1371/journal.pone.0082484

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