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Dendropanoxide Induces Autophagy through ERK1/2 Activation in MG-63 Human Osteosarcoma Cells and Autophagy Inhibition Enhances Dendropanoxide-Induced Apoptosis

Anticancer effects of dendropanoxide (DP) newly isolated from leaves and stem of Dendropanax morbifera Leveille were firstly investigated in this study. DP inhibited cell proliferation and induced apoptosis in dose- and time-dependent manner in MG-63 human osteosarcoma cells, which was dependent on...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Won, Kim, Kyoung-Sook, An, Hyun-Kyu, Kim, Cheorl-Ho, Moon, Hyung-In, Lee, Young-Choon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866153/
https://www.ncbi.nlm.nih.gov/pubmed/24358301
http://dx.doi.org/10.1371/journal.pone.0083611