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Acquired drug resistance conferred by a KRAS gene mutation following the administration of cetuximab: a case report
BACKGROUND: Although a number of studies have reported acquired drug resistance due to administration of epidermal growth factor receptor antibody inhibitors, the underlying causes of this phenomenon remain unclear. CASE PRESENTATION: Here we report a case of a 75-year-old man with liver metastasis...
Autores principales: | Osumi, Hiroki, Matsusaka, Satoshi, Shinozaki, Eiji, Suenaga, Mitsukuni, Mingyon, Mun, Saiura, Akio, Ueno, Masashi, Mizunuma, Nobuyuki, Yamaguchi, Toshiharu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866299/ https://www.ncbi.nlm.nih.gov/pubmed/24304820 http://dx.doi.org/10.1186/1756-0500-6-508 |
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