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Effects of two weeks of metformin treatment on whole-body glycocalyx barrier properties in db/db mice
BACKGROUND: The anti-diabetic drug metformin has been demonstrated to exert a protective effect against vascular complications in diabetes independent of its glucose lowering action. Since the endothelial glycocalyx has been indicated to have important vasculoprotective properties and to be vulnerab...
Autores principales: | Eskens, Bart JM, Zuurbier, Coert J, van Haare, Judith, Vink, Hans, van Teeffelen, Jurgen WGE |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866460/ https://www.ncbi.nlm.nih.gov/pubmed/24308370 http://dx.doi.org/10.1186/1475-2840-12-175 |
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