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Defining a new vision for the retinoblastoma gene: report from the 3rd International Rb Meeting
The retinoblastoma tumor suppressor (Rb) pathway is mutated in most, if not all human tumors. In the G0/G1 phase, Rb and its family members p107 and p130 inhibit the E2F family of transcription factors. In response to mitogenic signals, Cyclin-dependent kinases (CDKs) phosphorylate Rb family members...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866465/ https://www.ncbi.nlm.nih.gov/pubmed/24257515 http://dx.doi.org/10.1186/1747-1028-8-13 |