Stem Cell Isolation from Human Wharton’s Jelly: A Study of Their Differentiation Ability into Lens Fiber Cells

Recently, the use of stem cells has expanded into numerous areas including cell therapy. In this study, we investigated the differentiation capacity of human Wharton’s jelly stem cells (hWJSCs) into lens fiber cells. Morphological changes and expressions of four crystallin genes (αA, αB, βB1 and βB3...

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Autores principales: Khatami, Seyedeh Mahsa, Zahri, Saber, Maleki, Masoud, Hamidi, Kamaloddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866541/
https://www.ncbi.nlm.nih.gov/pubmed/24381862
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author Khatami, Seyedeh Mahsa
Zahri, Saber
Maleki, Masoud
Hamidi, Kamaloddin
author_facet Khatami, Seyedeh Mahsa
Zahri, Saber
Maleki, Masoud
Hamidi, Kamaloddin
author_sort Khatami, Seyedeh Mahsa
collection PubMed
description Recently, the use of stem cells has expanded into numerous areas including cell therapy. In this study, we investigated the differentiation capacity of human Wharton’s jelly stem cells (hWJSCs) into lens fiber cells. Morphological changes and expressions of four crystallin genes (αA, αB, βB1 and βB3) were studied. The bovine vitreous body has been shown to induce expression of crystallin genes in hWJSCs. By using the vitreous as a lens fiber cell inducer, we showed that αB-, βB1- and βB3-crystallin genes expressed in hWJSCs.
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spelling pubmed-38665412014-01-01 Stem Cell Isolation from Human Wharton’s Jelly: A Study of Their Differentiation Ability into Lens Fiber Cells Khatami, Seyedeh Mahsa Zahri, Saber Maleki, Masoud Hamidi, Kamaloddin Cell J Short Communication Recently, the use of stem cells has expanded into numerous areas including cell therapy. In this study, we investigated the differentiation capacity of human Wharton’s jelly stem cells (hWJSCs) into lens fiber cells. Morphological changes and expressions of four crystallin genes (αA, αB, βB1 and βB3) were studied. The bovine vitreous body has been shown to induce expression of crystallin genes in hWJSCs. By using the vitreous as a lens fiber cell inducer, we showed that αB-, βB1- and βB3-crystallin genes expressed in hWJSCs. Royan Institute 2014 2013-11-20 /pmc/articles/PMC3866541/ /pubmed/24381862 Text en Any use, distribution, reproduction or abstract of this publication in any medium, with the exception of commercial purposes, is permitted provided the original work is properly cited http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Khatami, Seyedeh Mahsa
Zahri, Saber
Maleki, Masoud
Hamidi, Kamaloddin
Stem Cell Isolation from Human Wharton’s Jelly: A Study of Their Differentiation Ability into Lens Fiber Cells
title Stem Cell Isolation from Human Wharton’s Jelly: A Study of Their Differentiation Ability into Lens Fiber Cells
title_full Stem Cell Isolation from Human Wharton’s Jelly: A Study of Their Differentiation Ability into Lens Fiber Cells
title_fullStr Stem Cell Isolation from Human Wharton’s Jelly: A Study of Their Differentiation Ability into Lens Fiber Cells
title_full_unstemmed Stem Cell Isolation from Human Wharton’s Jelly: A Study of Their Differentiation Ability into Lens Fiber Cells
title_short Stem Cell Isolation from Human Wharton’s Jelly: A Study of Their Differentiation Ability into Lens Fiber Cells
title_sort stem cell isolation from human wharton’s jelly: a study of their differentiation ability into lens fiber cells
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866541/
https://www.ncbi.nlm.nih.gov/pubmed/24381862
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