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Nd(3+) Sensitized Up/Down Converting Dual-Mode Nanomaterials for Efficient In-vitro and In-vivo Bioimaging Excited at 800 nm

Core/shell1/shell2/shell3 structured NaGdF(4):Nd/NaYF(4)/NaGdF(4):Nd,Yb,Er/NaYF(4) nanocrystals were well designed and synthesized, each of the parts assume respective role and work together to achieve dual-mode upconverting (UC) and downconverting (DC) luminescence upon the low heat effect 800-nm e...

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Autores principales: Li, Xiaomin, Wang, Rui, Zhang, Fan, Zhou, Lei, Shen, Dengke, Yao, Chi, Zhao, Dongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866591/
https://www.ncbi.nlm.nih.gov/pubmed/24346622
http://dx.doi.org/10.1038/srep03536
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author Li, Xiaomin
Wang, Rui
Zhang, Fan
Zhou, Lei
Shen, Dengke
Yao, Chi
Zhao, Dongyuan
author_facet Li, Xiaomin
Wang, Rui
Zhang, Fan
Zhou, Lei
Shen, Dengke
Yao, Chi
Zhao, Dongyuan
author_sort Li, Xiaomin
collection PubMed
description Core/shell1/shell2/shell3 structured NaGdF(4):Nd/NaYF(4)/NaGdF(4):Nd,Yb,Er/NaYF(4) nanocrystals were well designed and synthesized, each of the parts assume respective role and work together to achieve dual-mode upconverting (UC) and downconverting (DC) luminescence upon the low heat effect 800-nm excitation. Nd(3+), Yb(3+), Er(3+) tri-doped NaGdF(4):Nd,Yb,Er UC layer [NIR (800 nm)-to-Visible (540 nm)] with a constitutional efficient 800 nm excitable property were achieved for the in-vitro bioimaging with low auto-fluorescence and photo-damage effects. Moreover, typical NIR (800 nm)-to-NIR (860–895 nm) DC luminescence of Nd(3+) has also been realized with this designed nanostructure. Due to the low heat effect, high penetration depth of the excitation and the high efficiency of the DC luminescence, the in-vivo high contrast DC imaging of a whole body nude mouse was achieved. We believe that such dual-mode luminescence NCs will open the door to engineering the excitation and emission wavelengths of NCs and will provide a new tool for a wide variety of applications in the fields of bioanalysis and biomedical.
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spelling pubmed-38665912013-12-20 Nd(3+) Sensitized Up/Down Converting Dual-Mode Nanomaterials for Efficient In-vitro and In-vivo Bioimaging Excited at 800 nm Li, Xiaomin Wang, Rui Zhang, Fan Zhou, Lei Shen, Dengke Yao, Chi Zhao, Dongyuan Sci Rep Article Core/shell1/shell2/shell3 structured NaGdF(4):Nd/NaYF(4)/NaGdF(4):Nd,Yb,Er/NaYF(4) nanocrystals were well designed and synthesized, each of the parts assume respective role and work together to achieve dual-mode upconverting (UC) and downconverting (DC) luminescence upon the low heat effect 800-nm excitation. Nd(3+), Yb(3+), Er(3+) tri-doped NaGdF(4):Nd,Yb,Er UC layer [NIR (800 nm)-to-Visible (540 nm)] with a constitutional efficient 800 nm excitable property were achieved for the in-vitro bioimaging with low auto-fluorescence and photo-damage effects. Moreover, typical NIR (800 nm)-to-NIR (860–895 nm) DC luminescence of Nd(3+) has also been realized with this designed nanostructure. Due to the low heat effect, high penetration depth of the excitation and the high efficiency of the DC luminescence, the in-vivo high contrast DC imaging of a whole body nude mouse was achieved. We believe that such dual-mode luminescence NCs will open the door to engineering the excitation and emission wavelengths of NCs and will provide a new tool for a wide variety of applications in the fields of bioanalysis and biomedical. Nature Publishing Group 2013-12-18 /pmc/articles/PMC3866591/ /pubmed/24346622 http://dx.doi.org/10.1038/srep03536 Text en Copyright © 2013, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-sa/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-ShareALike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Article
Li, Xiaomin
Wang, Rui
Zhang, Fan
Zhou, Lei
Shen, Dengke
Yao, Chi
Zhao, Dongyuan
Nd(3+) Sensitized Up/Down Converting Dual-Mode Nanomaterials for Efficient In-vitro and In-vivo Bioimaging Excited at 800 nm
title Nd(3+) Sensitized Up/Down Converting Dual-Mode Nanomaterials for Efficient In-vitro and In-vivo Bioimaging Excited at 800 nm
title_full Nd(3+) Sensitized Up/Down Converting Dual-Mode Nanomaterials for Efficient In-vitro and In-vivo Bioimaging Excited at 800 nm
title_fullStr Nd(3+) Sensitized Up/Down Converting Dual-Mode Nanomaterials for Efficient In-vitro and In-vivo Bioimaging Excited at 800 nm
title_full_unstemmed Nd(3+) Sensitized Up/Down Converting Dual-Mode Nanomaterials for Efficient In-vitro and In-vivo Bioimaging Excited at 800 nm
title_short Nd(3+) Sensitized Up/Down Converting Dual-Mode Nanomaterials for Efficient In-vitro and In-vivo Bioimaging Excited at 800 nm
title_sort nd(3+) sensitized up/down converting dual-mode nanomaterials for efficient in-vitro and in-vivo bioimaging excited at 800 nm
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866591/
https://www.ncbi.nlm.nih.gov/pubmed/24346622
http://dx.doi.org/10.1038/srep03536
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