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Dysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness

Molecular abnormalities within the glucocorticoid receptor (GR) stress signaling pathway may confer, or reflect, susceptibility to stress in schizophrenia and bipolar disorder, but the extent of such abnormalities in the brain is not known. Using RNA-Seq and qPCR in two postmortem cohorts totaling 5...

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Detalles Bibliográficos
Autores principales: Sinclair, Duncan, Fillman, Stu G., Webster, Maree J., Weickert, Cynthia Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866598/
https://www.ncbi.nlm.nih.gov/pubmed/24345775
http://dx.doi.org/10.1038/srep03539

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