Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis

Glycoconjugate-based vaccines have proved to be effective at producing long-lasting protection against numerous pathogens. Here, we describe the application of bacterial protein glycan coupling technology (PGCT) to generate a novel recombinant glycoconjugate vaccine. We demonstrate the conjugation o...

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Detalles Bibliográficos
Autores principales: Cuccui, Jon, Thomas, Rebecca M., Moule, Madeleine G., D'Elia, Riccardo V., Laws, Thomas R., Mills, Dominic C., Williamson, Diane, Atkins, Timothy P., Prior, Joann L., Wren, Brendan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866875/
https://www.ncbi.nlm.nih.gov/pubmed/23697804
http://dx.doi.org/10.1098/rsob.130002

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