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Regulatory T cell stability is maintained by a neuropilin-1:semaphorin-4a axis

Regulatory T cells (T(regs)) play a crucial role in the immune system by preventing autoimmunity, limiting immunopathology, and maintaining immune homeostasis(1). However, they also represent a major barrier to effective anti-tumor immunity and sterilizing immunity to chronic viral infections(1). Th...

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Detalles Bibliográficos
Autores principales: Delgoffe, Greg M., Woo, Seng-Ryong, Turnis, Meghan E., Gravano, David M., Guy, Cliff, Overacre, Abigail E., Bettini, Matthew L., Vogel, Peter, Finkelstein, David, Bonnevier, Jody, Workman, Creg J., Vignali, Dario A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867145/
https://www.ncbi.nlm.nih.gov/pubmed/23913274
http://dx.doi.org/10.1038/nature12428

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