Cargando…
Regulatory T cell stability is maintained by a neuropilin-1:semaphorin-4a axis
Regulatory T cells (T(regs)) play a crucial role in the immune system by preventing autoimmunity, limiting immunopathology, and maintaining immune homeostasis(1). However, they also represent a major barrier to effective anti-tumor immunity and sterilizing immunity to chronic viral infections(1). Th...
Autores principales: | Delgoffe, Greg M., Woo, Seng-Ryong, Turnis, Meghan E., Gravano, David M., Guy, Cliff, Overacre, Abigail E., Bettini, Matthew L., Vogel, Peter, Finkelstein, David, Bonnevier, Jody, Workman, Creg J., Vignali, Dario A.A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867145/ https://www.ncbi.nlm.nih.gov/pubmed/23913274 http://dx.doi.org/10.1038/nature12428 |
Ejemplares similares
-
Elucidating the role of Neuropilin-1 in intra-tumoral regulatory T cell stability
por: Overacre, Abigail E, et al.
Publicado: (2015) -
Neuropilin-1: a checkpoint target with unique implications for cancer immunology and immunotherapy
por: Chuckran, Christopher A, et al.
Publicado: (2020) -
Expression of Semaphorin 3A and Neuropilin 1 in Asthma
por: Shim, Eun-Jin, et al.
Publicado: (2013) -
The emerging role of class-3 semaphorins and their neuropilin receptors in oncology
por: Nasarre, Patrick, et al.
Publicado: (2014) -
Current drug design to target the Semaphorin/Neuropilin/Plexin complexes
por: Meyer, Lionel A. T., et al.
Publicado: (2016)