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Decision-Tree Based Model Analysis for Efficient Identification of Parameter Relations Leading to Different Signaling States
In systems biology, a mathematical description of signal transduction processes is used to gain a more detailed mechanistic understanding of cellular signaling networks. Such models typically depend on a number of parameters that have different influence on the model behavior. Local sensitivity anal...
Autores principales: | Koch, Yvonne, Wolf, Thomas, Sorger, Peter K., Eils, Roland, Brors, Benedikt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867358/ https://www.ncbi.nlm.nih.gov/pubmed/24367526 http://dx.doi.org/10.1371/journal.pone.0082593 |
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