Cargando…
The paternally imprinted DLK1-GTL2 locus is differentially methylated in embryonal and alveolar rhabdomyosarcomas
Parental imprinting of differentially methylated regions (DMRs) contributes to appropriate expression of several developmentally important genes from paternally or maternally derived chromosomes. Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children and is associated with altered...
Autores principales: | SCHNEIDER, GABRIELA, BOWSER, MARK J., SHIN, DONG-MYUNG, BARR, FREDERIC G., RATAJCZAK, MARIUSZ Z. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867365/ https://www.ncbi.nlm.nih.gov/pubmed/24173021 http://dx.doi.org/10.3892/ijo.2013.2153 |
Ejemplares similares
-
Loss of imprinting at the Dlk1-Gtl2 locus caused by insertional mutagenesis in the Gtl2 5' region
por: Steshina, Ekaterina Y, et al.
Publicado: (2006) -
Expression at the Imprinted Dlk1-Gtl2 Locus Is Regulated by Proneural Genes in the Developing Telencephalon
por: Seibt, Julie, et al.
Publicado: (2012) -
Deletion of conserved sequences in IG-DMR at Dlk1-Gtl2 locus suggests their involvement in expression of
paternally expressed genes in mice
por: SAITO, Takeshi, et al.
Publicado: (2016) -
Hypermethylation and reduced expression of Gtl2, Rian and Mirg at the Dlk1-Dio3 imprinted locus as a marker for poor developmental potential of mouse embryonic stem cells
por: Schacker, Maria, et al.
Publicado: (2020) -
Imprinted Dlk1-Gtl2 cluster miRNAs are potential epigenetic regulators of lamb fur quality
por: Zhang, Letian, et al.
Publicado: (2023)