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Burden of micronutrient deficiencies by socio-economic strata in children aged 6 months to 5 years in the Philippines

BACKGROUND: Micronutrient deficiencies (MNDs) are a chronic lack of vitamins and minerals and constitute a huge public health problem. MNDs have severe health consequences and are particularly harmful during early childhood due to their impact on the physical and cognitive development. We estimate t...

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Autores principales: Wieser, Simon, Plessow, Rafael, Eichler, Klaus, Malek, Olivia, Capanzana, Mario V, Agdeppa, Imelda, Bruegger, Urs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867423/
https://www.ncbi.nlm.nih.gov/pubmed/24330481
http://dx.doi.org/10.1186/1471-2458-13-1167
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author Wieser, Simon
Plessow, Rafael
Eichler, Klaus
Malek, Olivia
Capanzana, Mario V
Agdeppa, Imelda
Bruegger, Urs
author_facet Wieser, Simon
Plessow, Rafael
Eichler, Klaus
Malek, Olivia
Capanzana, Mario V
Agdeppa, Imelda
Bruegger, Urs
author_sort Wieser, Simon
collection PubMed
description BACKGROUND: Micronutrient deficiencies (MNDs) are a chronic lack of vitamins and minerals and constitute a huge public health problem. MNDs have severe health consequences and are particularly harmful during early childhood due to their impact on the physical and cognitive development. We estimate the costs of illness due to iron deficiency (IDA), vitamin A deficiency (VAD) and zinc deficiency (ZnD) in 2 age groups (6–23 and 24–59 months) of Filipino children by socio-economic strata in 2008. METHODS: We build a health economic model simulating the consequences of MNDs in childhood over the entire lifetime. The model is based on a health survey and a nutrition survey carried out in 2008. The sample populations are first structured into 10 socio-economic strata (SES) and 2 age groups. Health consequences of MNDs are modelled based on information extracted from literature. Direct medical costs, production losses and intangible costs are computed and long term costs are discounted to present value. RESULTS: Total lifetime costs of IDA, VAD and ZnD amounted to direct medical costs of 30 million dollars, production losses of 618 million dollars and intangible costs of 122,138 disability adjusted life years (DALYs). These costs can be interpreted as the lifetime costs of a 1-year cohort affected by MNDs between the age of 6–59 months. Direct medical costs are dominated by costs due to ZnD (89% of total), production losses by losses in future lifetime (90% of total) and intangible costs by premature death (47% of total DALY losses) and losses in future lifetime (43%). Costs of MNDs differ considerably between SES as costs in the poorest third of the households are 5 times higher than in the wealthiest third. CONCLUSIONS: MNDs lead to substantial costs in 6-59-month-old children in the Philippines. Costs are highly concentrated in the lower SES and in children 6–23 months old. These results may have important implications for the design, evaluation and choice of the most effective and cost-effective policies aimed at the reduction of MNDs.
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spelling pubmed-38674232013-12-19 Burden of micronutrient deficiencies by socio-economic strata in children aged 6 months to 5 years in the Philippines Wieser, Simon Plessow, Rafael Eichler, Klaus Malek, Olivia Capanzana, Mario V Agdeppa, Imelda Bruegger, Urs BMC Public Health Research Article BACKGROUND: Micronutrient deficiencies (MNDs) are a chronic lack of vitamins and minerals and constitute a huge public health problem. MNDs have severe health consequences and are particularly harmful during early childhood due to their impact on the physical and cognitive development. We estimate the costs of illness due to iron deficiency (IDA), vitamin A deficiency (VAD) and zinc deficiency (ZnD) in 2 age groups (6–23 and 24–59 months) of Filipino children by socio-economic strata in 2008. METHODS: We build a health economic model simulating the consequences of MNDs in childhood over the entire lifetime. The model is based on a health survey and a nutrition survey carried out in 2008. The sample populations are first structured into 10 socio-economic strata (SES) and 2 age groups. Health consequences of MNDs are modelled based on information extracted from literature. Direct medical costs, production losses and intangible costs are computed and long term costs are discounted to present value. RESULTS: Total lifetime costs of IDA, VAD and ZnD amounted to direct medical costs of 30 million dollars, production losses of 618 million dollars and intangible costs of 122,138 disability adjusted life years (DALYs). These costs can be interpreted as the lifetime costs of a 1-year cohort affected by MNDs between the age of 6–59 months. Direct medical costs are dominated by costs due to ZnD (89% of total), production losses by losses in future lifetime (90% of total) and intangible costs by premature death (47% of total DALY losses) and losses in future lifetime (43%). Costs of MNDs differ considerably between SES as costs in the poorest third of the households are 5 times higher than in the wealthiest third. CONCLUSIONS: MNDs lead to substantial costs in 6-59-month-old children in the Philippines. Costs are highly concentrated in the lower SES and in children 6–23 months old. These results may have important implications for the design, evaluation and choice of the most effective and cost-effective policies aimed at the reduction of MNDs. BioMed Central 2013-12-11 /pmc/articles/PMC3867423/ /pubmed/24330481 http://dx.doi.org/10.1186/1471-2458-13-1167 Text en Copyright © 2013 Wieser et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wieser, Simon
Plessow, Rafael
Eichler, Klaus
Malek, Olivia
Capanzana, Mario V
Agdeppa, Imelda
Bruegger, Urs
Burden of micronutrient deficiencies by socio-economic strata in children aged 6 months to 5 years in the Philippines
title Burden of micronutrient deficiencies by socio-economic strata in children aged 6 months to 5 years in the Philippines
title_full Burden of micronutrient deficiencies by socio-economic strata in children aged 6 months to 5 years in the Philippines
title_fullStr Burden of micronutrient deficiencies by socio-economic strata in children aged 6 months to 5 years in the Philippines
title_full_unstemmed Burden of micronutrient deficiencies by socio-economic strata in children aged 6 months to 5 years in the Philippines
title_short Burden of micronutrient deficiencies by socio-economic strata in children aged 6 months to 5 years in the Philippines
title_sort burden of micronutrient deficiencies by socio-economic strata in children aged 6 months to 5 years in the philippines
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867423/
https://www.ncbi.nlm.nih.gov/pubmed/24330481
http://dx.doi.org/10.1186/1471-2458-13-1167
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