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ESR1 Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous

Prevalence of ESR1 amplification in breast cancer is highly disputed and discrepancies have been related to different technical protocols and different scoring approaches. In addition, pre-mRNA artifacts have been proposed to influence outcome of ESR1 FISH analysis. We analyzed ESR1 gene copy number...

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Detalles Bibliográficos
Autores principales:	Moelans, Cathy B., Holst, Frederik, Hellwinkel, Olaf, Simon, Ronald, van Diest, Paul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867473/ https://www.ncbi.nlm.nih.gov/pubmed/24367641 http://dx.doi.org/10.1371/journal.pone.0084189

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