PEDF Expression Is Inhibited by Insulin Treatment in Adipose Tissue via Suppressing 11β-HSD1

Early intensive insulin therapy improves insulin sensitivity in type 2 diabetic patients; while the underlying mechanism remains largely unknown. Pigment epithelium-derived factor (PEDF), an anti-angiogenic factor, is believed to be involved in the pathogenesis of insulin resistance. Here, we hypoth...

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Detalles Bibliográficos
Autores principales: Zhou, Yinli, Xu, Fen, Deng, Hongrong, Bi, Yan, Sun, Weiping, Zhao, Yi, Chen, Zonglan, Weng, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867502/
https://www.ncbi.nlm.nih.gov/pubmed/24367624
http://dx.doi.org/10.1371/journal.pone.0084016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867502/
https://www.ncbi.nlm.nih.gov/pubmed/24367624
http://dx.doi.org/10.1371/journal.pone.0084016

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