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The Roles of Notch3 on the Cell Proliferation and Apoptosis Induced by CHIR99021 in NSCLC Cell Lines: A Functional Link between Wnt and Notch Signaling Pathways

Wnt and Notch signaling pathways both play essential roles and interact closely in development and carcinogenesis, but their interaction in non-small-cell lung cancer (NSCLC) is poorly unknown. Here we investigated the effects of CHIR99021, a Wnt signaling agonist, or Notch3-shRNA, or the combined a...

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Detalles Bibliográficos
Autores principales:	Li, Chunyan, Zhang, Siyang, Lu, Yao, Zhang, Ying, Wang, Enhua, Cui, Zeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867546/ https://www.ncbi.nlm.nih.gov/pubmed/24367688 http://dx.doi.org/10.1371/journal.pone.0084659

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