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A Homology Based Model and Virtual Screening of Inhibitors for Human Geranylgeranyl Transferase 1 (GGTase1)

Protein prenylation is a post translational modification that is indispensable for Ras–Rho mediated tumorigenesis. In mammals, three enzymes namely protein farnesyltransferase (FTase), geranylgeranyl transferase1 (GGTase1), and geranylgeranyl transferase2 (GGTase2) were found to be involved in this...

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Detalles Bibliográficos
Autores principales:	Thippanna, Mallikarjuna, Subramani, Parasuraman Aiya, Lomada, Dakshayani, Narala, Venkata Ramireddy, Reddy, Madhava C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2013
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867650/ https://www.ncbi.nlm.nih.gov/pubmed/24391360 http://dx.doi.org/10.6026/97320630009973

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