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Proteomic Analysis of PTCH1+/− Fibroblast Lysate and Conditioned Culture Media Isolated from the Skin of Healthy Subjects and Nevoid Basal Cell Carcinoma Syndrome Patients

Background. The pathogenesis underlying the increased predisposition to the development of basal cell carcinomas (BCCs) in the context of Gorlin-Goltz syndrome is linked to molecular mechanisms that differ from sporadic BCCs. Patients with Gorlin syndrome tend to develop multiple BCCs at an early ag...

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Detalles Bibliográficos
Autores principales: Ponti, Giovanni, Bertazzoni, Giorgia, Pastorino, Lorenza, Monari, Emanuela, Cuoghi, Aurora, Bergamini, Stefania, Bellei, Elisa, Benassi, Luisa, Azzoni, Paola, Petrachi, Tiziana, Magnoni, Cristina, Pellacani, Giovanni, Loschi, Pietro, Pollio, Annamaria, Witkowski, Alexander Michael, Tomasi, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867831/
https://www.ncbi.nlm.nih.gov/pubmed/24369017
http://dx.doi.org/10.1155/2013/794028