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Both Acyl and Des-Acyl Ghrelin Regulate Adiposity and Glucose Metabolism via Central Nervous System Ghrelin Receptors

Growth hormone secretagogue receptors (GHSRs) in the central nervous system (CNS) mediate hyperphagia and adiposity induced by acyl ghrelin (AG). Evidence suggests that des-AG (dAG) has biological activity through GHSR-independent mechanisms. We combined in vitro and in vivo approaches to test possi...

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Detalles Bibliográficos
Autores principales:	Heppner, Kristy M., Piechowski, Carolin L., Müller, Anne, Ottaway, Nickki, Sisley, Stephanie, Smiley, David L., Habegger, Kirk M., Pfluger, Paul T., DiMarchi, Richard, Biebermann, Heike, Tschöp, Matthias H., Sandoval, Darleen A., Perez-Tilve, Diego
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2014
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868046/ https://www.ncbi.nlm.nih.gov/pubmed/24062249 http://dx.doi.org/10.2337/db13-0414

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