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Knockdown of Glyoxalase 1 Mimics Diabetic Nephropathy in Nondiabetic Mice

Differences in susceptibility to diabetic nephropathy (DN) between mouse strains with identical levels of hyperglycemia correlate with renal levels of oxidative stress, shown previously to play a central role in the pathogenesis of DN. Susceptibility to DN appears to be genetically determined, but t...

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Detalles Bibliográficos
Autores principales:	Giacco, Ferdinando, Du, Xueliang, D’Agati, Vivette D., Milne, Ross, Sui, Guangzhi, Geoffrion, Michele, Brownlee, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2014
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868051/ https://www.ncbi.nlm.nih.gov/pubmed/24062246 http://dx.doi.org/10.2337/db13-0316

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