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Constitutively Active CaMKKα Stimulates Skeletal Muscle Glucose Uptake in Insulin-Resistant Mice In Vivo
In insulin-sensitive skeletal muscle, the expression of constitutively active Ca(2+)/calmodulin-dependent protein kinase kinase α (caCaMKKα) stimulates glucose uptake independent of insulin signaling (i.e., Akt and Akt-dependent TBC1D1/TBC1D4 phosphorylation). Our objectives were to determine whethe...
Autores principales: | Hinkley, J. Matthew, Ferey, Jeremie L., Brault, Jeffrey J., Smith, Cheryl A.S., Gilliam, Laura A.A., Witczak, Carol A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868053/ https://www.ncbi.nlm.nih.gov/pubmed/24101676 http://dx.doi.org/10.2337/db13-0452 |
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