Cargando…

Thymoquinone regulates gene expression levels in the estrogen metabolic and interferon pathways in MCF7 breast cancer cells

New drugs are continuously being developed for the treatment of patients with estrogen receptor-positive breast cancer. Thymoquinone is one of the drugs that exhibits anticancer characteristics based on in vivo and in vitro models. This study further investigates the effects of thymoquinone on human...

Descripción completa

Detalles Bibliográficos
Autores principales:	MOTAGHED, MARJANEH, AL-HASSAN, FAISAL MUTI, HAMID, SHAHRUL SAHUL
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868490/ https://www.ncbi.nlm.nih.gov/pubmed/24270600 http://dx.doi.org/10.3892/ijmm.2013.1563

Ejemplares similares

Cellular responses with thymoquinone treatment in human breast cancer cell line MCF-7
por: Motaghed, Marjaneh, et al.
Publicado: (2013)

The Influence of Pluronic F68 and F127 Nanocarrier on Physicochemical Properties, In vitro Release, and Antiproliferative Activity of Thymoquinone Drug
por: Shaarani, Salwa, et al.
Publicado: (2017)

Formulation, Characterization and Cytotoxicity Effects of Novel Thymoquinone-PLGA-PF68 Nanoparticles
por: Noor, Nurul Shahfiza, et al.
Publicado: (2021)

Co-encapsulation of thymoquinone with docetaxel enhances the encapsulation efficiency into PEGylated liposomes and the chemosensitivity of MCF7 breast cancer cells to docetaxel
por: Odeh, Fadwa, et al.
Publicado: (2019)

Combination of Goniothalamin and Sol-Gel-Derived Bioactive Glass 45S5 Enhances Growth Inhibitory Activity via Apoptosis Induction and Cell Cycle Arrest in Breast Cancer Cells MCF-7
por: Bakar, Siti Aishah Abu, et al.
Publicado: (2022)

Interaction of Vault Particles with Estrogen Receptor in the MCF-7 Breast Cancer Cell
por: Abbondanza, Ciro, et al.
Publicado: (1998)

Luteolin Regulation of Estrogen Signaling and Cell Cycle Pathway Genes in MCF-7 Human Breast Cancer Cells
por: Markaverich, Barry M., et al.
Publicado: (2011)

Estrogen Sulfotransferase Induction Inhibits Breast Cancer Cell Line MCF-7 Proliferation
por: Jiang, Weiyu, et al.
Publicado: (2019)

Lipoproteins as Markers for Monitoring Cancer Progression
por: Maran, Logeswaran, et al.
Publicado: (2021)

Beetroot as a Potential Functional Food for Cancer Chemoprevention, a Narrative Review
por: Tan, Mei Lan, et al.
Publicado: (2021)

Estrogen-Like Properties of Fluorotelomer Alcohols as Revealed by MCF-7 Breast Cancer Cell Proliferation
por: Maras, Marleen, et al.
Publicado: (2006)

Estrogenic potential of certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line.
por: Go, V, et al.
Publicado: (1999)

Expression profiling of genes modulated by estrogen, EGCG or both in MCF-7 breast cancer cells
por: Manjegowda, Mohan C., et al.
Publicado: (2015)

Estrogen regulation and ion dependence of taurine uptake by MCF-7 human breast cancer cells
por: Shennan, David B., et al.
Publicado: (2007)

Metabolic Profiling Reveals Sphingosine-1-Phosphate Kinase 2 and Lyase as Key Targets of (Phyto-) Estrogen Action in the Breast Cancer Cell Line MCF-7 and Not in MCF-12A
por: Engel, Nadja, et al.
Publicado: (2012)

Cytotoxicity and Apoptosis Induced by a Plumbagin Derivative in Estrogen Positive MCF-7 Breast Cancer Cells
por: Sagar, Sunil, et al.
Publicado: (2014)

Estrogen stimulates adenosine receptor expression subtypes in human breast cancer MCF-7 cell line
por: Mohamadi, Azam, et al.
Publicado: (2018)

Inhibition of Nicotinamide Phosphoribosyltransferase Induces Apoptosis in Estrogen Receptor-Positive MCF-7 Breast Cancer Cells
por: Alaee, Mohammad, et al.
Publicado: (2017)

A Chip for Estrogen Receptor Action: Detection of Biomarkers Released by MCF-7 Cells through Estrogenic and Anti-Estrogenic Effects
por: Gier, Konstanze, et al.
Publicado: (2017)

Cytotoxic and chemomodulatory effects of Phyllanthus niruri in MCF-7 and MCF-7(ADR) breast cancer cells
por: Abdel-Sattar, Ola E., et al.
Publicado: (2023)

Evaluation of Cell Cycle Arrest in Estrogen Responsive MCF-7 Breast Cancer Cells: Pitfalls of the MTS Assay
por: McGowan, Eileen M., et al.
Publicado: (2011)

Tetrahydro-iso-alpha Acids Antagonize Estrogen Receptor Alpha Activity in MCF-7 Breast Cancer Cells
por: Lempereur, Maëlle, et al.
Publicado: (2016)

Combination of Cyclopamine and Tamoxifen Promotes Survival and Migration of MCF-7 Breast Cancer Cells – Interaction of Hedgehog-Gli and Estrogen Receptor Signaling Pathways
por: Sabol, Maja, et al.
Publicado: (2014)

Untargeted Metabolomics Identifies Key Metabolic Pathways Altered by Thymoquinone in Leukemic Cancer Cells
por: AlGhamdi, Asma Ahmed, et al.
Publicado: (2020)

Membrane estrogen receptor-α levels predict estrogen-induced ERK1/2 activation in MCF-7 cells
por: Zivadinovic, Dragoslava, et al.
Publicado: (2005)

Iodine Alters Gene Expression in the MCF7 Breast Cancer Cell Line: Evidence for an Anti-Estrogen Effect of Iodine
por: Stoddard II, Frederick R., et al.
Publicado: (2008)

Membrane estrogen receptor-α levels in MCF-7 breast cancer cells predict cAMP and proliferation responses
por: Zivadinovic, Dragoslava, et al.
Publicado: (2005)

Oxidative Stress-Mediated Apoptosis Induced by Ethanolic Mango Seed Extract in Cultured Estrogen Receptor Positive Breast Cancer MCF-7 Cells
por: Abdullah, Al-Shwyeh Hussah, et al.
Publicado: (2015)

Embelin-induced MCF-7 breast cancer cell apoptosis and blockade of MCF-7 cells in the G2/M phase via the mitochondrial pathway
por: LI, YANG, et al.
Publicado: (2013)

IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function
por: Ambjørn, Malene, et al.
Publicado: (2013)

Metabolic reprogramming by Dichloroacetic acid potentiates photodynamic therapy of human breast adenocarcinoma MCF-7 cells
por: Alkarakooly, Zeiyad, et al.
Publicado: (2018)

Two Estrogen Response Element Sequences Near the PCNA Gene Are Not Responsible for Its Estrogen-Enhanced Expression in MCF7 Cells
por: Wang, Cheng, et al.
Publicado: (2008)

Downregulation of Steroid Receptor Coactivator-2 Modulates Estrogen-Responsive Genes and Stimulates Proliferation of MCF-7 Breast Cancer Cells
por: Fenne, Ingvild S., et al.
Publicado: (2013)

Ligand-free estrogen receptor activity complements IGF1R to induce the proliferation of the MCF-7 breast cancer cells
por: Gaben, Anne-Marie, et al.
Publicado: (2012)

Estrogen Regulates Mitochondrial Morphology through Phosphorylation of Dynamin-related Protein 1 in MCF7 Human Breast Cancer Cells
por: Oo, Phyu Synn, et al.
Publicado: (2018)

Estrogen-like activity of aqueous extract from Agrimonia pilosa Ledeb. in MCF-7 cells
por: Lee, Young Min, et al.
Publicado: (2012)

Estrogen Inhibits the Growth of MCF‐7 Cell Variants Resistant to Transforming Growth Factor‐beta
por: Hagino, Yoshiaki, et al.
Publicado: (1988)

Analysis of Estrogenic Activity in Maryland Coastal Bays Using the MCF-7 Cell Proliferation Assay
por: Elfadul, Rehab, et al.
Publicado: (2021)

Benzoquinone from Fusarium pigment inhibits the proliferation of estrogen receptor-positive MCF-7 cells through the NF-κB pathway via estrogen receptor signaling
por: Zheng, Lixiang, et al.
Publicado: (2017)

Certain styrene oligomers have proliferative activity on MCF-7 human breast tumor cells and binding affinity for human estrogen receptor.
por: Ohyama, K I, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_ekfo20ie69uvjbdrjfs61pior6