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In vivo analysis of insulin-like growth factor type 1 receptor humanized monoclonal antibody MK-0646 and small molecule kinase inhibitor OSI-906 in colorectal cancer

The development and characterization of effective anticancer drugs against colorectal cancer (CRC) is of urgent need since it is the second most common cause of cancer death. The study was designed to evaluate the effects of two IGF-1R antagonists, MK-0646, a recombinant fully humanized monoclonal a...

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Detalles Bibliográficos
Autores principales: LEIPHRAKPAM, PREMILA D., AGARWAL, EKTA, MATHIESEN, MICHELLE, HAFERBIER, KATIE L., BRATTAIN, MICHAEL G., CHOWDHURY, SANJIB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868504/
https://www.ncbi.nlm.nih.gov/pubmed/24173770
http://dx.doi.org/10.3892/or.2013.2819