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Toxoplasma gondii-Induced Activation of EGFR Prevents Autophagy Protein-Mediated Killing of the Parasite

Toxoplasma gondii resides in an intracellular compartment (parasitophorous vacuole) that excludes transmembrane molecules required for endosome - lysosome recruitment. Thus, the parasite survives by avoiding lysosomal degradation. However, autophagy can re-route the parasitophorous vacuole to the ly...

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Detalles Bibliográficos
Autores principales: Muniz-Feliciano, Luis, Van Grol, Jennifer, Portillo, Jose-Andres C., Liew, Lloyd, Liu, Bing, Carlin, Cathleen R., Carruthers, Vern B., Matthews, Stephen, Subauste, Carlos S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868508/
https://www.ncbi.nlm.nih.gov/pubmed/24367261
http://dx.doi.org/10.1371/journal.ppat.1003809