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Biphasic Euchromatin-to-Heterochromatin Transition on the KSHV Genome Following De Novo Infection
The establishment of latency is an essential step for the life-long persistent infection and pathogenesis of Kaposi's sarcoma-associated herpesvirus (KSHV). While the KSHV genome is chromatin-free in the virions, the viral DNA in latently infected cells has a chromatin structure with activating...
Autores principales: | Toth, Zsolt, Brulois, Kevin, Lee, Hye-Ra, Izumiya, Yoshihiro, Tepper, Clifford, Kung, Hsing-Jien, Jung, Jae U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868514/ https://www.ncbi.nlm.nih.gov/pubmed/24367262 http://dx.doi.org/10.1371/journal.ppat.1003813 |
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