Revisiting the Central Metabolism of the Bloodstream Forms of Trypanosoma brucei: Production of Acetate in the Mitochondrion Is Essential for Parasite Viability

BACKGROUND: The bloodstream forms of Trypanosoma brucei, the causative agent of sleeping sickness, rely solely on glycolysis for ATP production. It is generally accepted that pyruvate is the major end-product excreted from glucose metabolism by the proliferative long-slender bloodstream forms of the...

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Detalles Bibliográficos
Autores principales: Mazet, Muriel, Morand, Pauline, Biran, Marc, Bouyssou, Guillaume, Courtois, Pierrette, Daulouède, Sylvie, Millerioux, Yoann, Franconi, Jean-Michel, Vincendeau, Philippe, Moreau, Patrick, Bringaud, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868518/
https://www.ncbi.nlm.nih.gov/pubmed/24367711
http://dx.doi.org/10.1371/journal.pntd.0002587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868518/
https://www.ncbi.nlm.nih.gov/pubmed/24367711
http://dx.doi.org/10.1371/journal.pntd.0002587

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