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Pathophysiological Defects and Transcriptional Profiling in the RBM20(-/-) Rat Model

Our recent study indicated that RNA binding motif 20 (Rbm20) alters splicing of titin and other genes. The current goals were to understand how the Rbm20(-/-) rat is related to physiological, structural, and molecular changes leading to heart failure. We quantitatively and qualitatively compared the...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Pleitner, Jonathan M., Saupe, Kurt W., Greaser, Marion L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868568/
https://www.ncbi.nlm.nih.gov/pubmed/24367651
http://dx.doi.org/10.1371/journal.pone.0084281