The CCR4-NOT Complex Mediates Deadenylation and Degradation of Stem Cell mRNAs and Promotes Planarian Stem Cell Differentiation

Post-transcriptional regulatory mechanisms are of fundamental importance to form robust genetic networks, but their roles in stem cell pluripotency remain poorly understood. Here, we use freshwater planarians as a model system to investigate this and uncover a role for CCR4-NOT mediated deadenylatio...

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Detalles Bibliográficos
Autores principales: Solana, Jordi, Gamberi, Chiara, Mihaylova, Yuliana, Grosswendt, Stefanie, Chen, Chen, Lasko, Paul, Rajewsky, Nikolaus, Aboobaker, A. Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868585/
https://www.ncbi.nlm.nih.gov/pubmed/24367277
http://dx.doi.org/10.1371/journal.pgen.1004003

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