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A Penile Spine/Vibrissa Enhancer Sequence Is Missing in Modern and Extinct Humans but Is Retained in Multiple Primates with Penile Spines and Sensory Vibrissae
Previous studies show that humans have a large genomic deletion downstream of the Androgen Receptor gene that eliminates an ancestral mammalian regulatory enhancer that drives expression in developing penile spines and sensory vibrissae. Here we use a combination of large-scale sequence analysis and...
Autores principales: | Reno, Philip L., McLean, Cory Y., Hines, Jasmine E., Capellini, Terence D., Bejerano, Gill, Kingsley, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868586/ https://www.ncbi.nlm.nih.gov/pubmed/24367647 http://dx.doi.org/10.1371/journal.pone.0084258 |
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