C6-Ceramide Nanoliposomes Target the Warburg Effect in Chronic Lymphocytic Leukemia

Ceramide is a sphingolipid metabolite that induces cancer cell death. When C6-ceramide is encapsulated in a nanoliposome bilayer formulation, cell death is selectively induced in tumor models. However, the mechanism underlying this selectivity is unknown. As most tumors exhibit a preferential switch...

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Detalles Bibliográficos
Autores principales: Ryland, Lindsay K., Doshi, Ushma A., Shanmugavelandy, Sriram S., Fox, Todd E., Aliaga, Cesar, Broeg, Kathleen, Baab, Kendall Thomas, Young, Megan, Khan, Osman, Haakenson, Jeremy K., Jarbadan, Nancy Ruth, Liao, Jason, Wang, Hong-Gang, Feith, David J., Loughran Jr, Thomas P., Liu, Xin, Kester, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868606/
https://www.ncbi.nlm.nih.gov/pubmed/24367685
http://dx.doi.org/10.1371/journal.pone.0084648

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