Genome Sequences of 28 Bordetella pertussis U.S. Outbreak Strains Dating from 2010 to 2012

Despite the availability of highly effective vaccines, Bordetella pertussis incidence has been rapidly rising in highly vaccinated populations. Recent outbreaks have received media attention, feeding concerns about the emergence of dangerous new strains with increased virulence or that escape vaccin...

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Detalles Bibliográficos
Autores principales: Harvill, Eric T., Goodfield, Laura L., Ivanov, Yury, Meyer, Jessica A., Newth, Christopher, Cassiday, Pamela, Tondella, Maria Lucia, Liao, Patty, Zimmerman, Jerry, Meert, Kathleen, Wessel, David, Berger, John, Dean, J. Michael, Holubkov, Richard, Burr, Jeri, Liu, Teresa, Brinkac, Lauren, Kim, Maria, Losada, Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868863/
https://www.ncbi.nlm.nih.gov/pubmed/24356839
http://dx.doi.org/10.1128/genomeA.01075-13
Descripción
Sumario:Despite the availability of highly effective vaccines, Bordetella pertussis incidence has been rapidly rising in highly vaccinated populations. Recent outbreaks have received media attention, feeding concerns about the emergence of dangerous new strains with increased virulence or that escape vaccine-induced immunity. To accelerate the study of this reemerging pathogen, we sequenced the genomes of 28 B. pertussis strains isolated during outbreaks from 2010 through 2012, making both strains and sequence data available to the scientific community.

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