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CIITA and Its Dual Roles in MHC Gene Transcription

Class II transactivator (CIITA) is a transcriptional coactivator that regulates γ-interferon-activated transcription of Major Histocompatibility Complex (MHC) class I and II genes. As such, it plays a critical role in immune responses: CIITA deficiency results in aberrant MHC gene expression and con...

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Detalles Bibliográficos
Autores principales:	Devaiah, Ballachanda N., Singer, Dinah S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868913/ https://www.ncbi.nlm.nih.gov/pubmed/24391648 http://dx.doi.org/10.3389/fimmu.2013.00476

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