Interhelical loops within the bHLH domain are determinant in maintaining TWIST1–DNA complexes

The basic helix-loop-helix (bHLH) transcription factor TWIST1 is essential to embryonic development, and hijacking of its function contributes to the development of numerous cancer types. It forms either a homodimer or a heterodimeric complex with an E2A or HAND partner. These functionally distinct...

Descripción completa

Detalles Bibliográficos
Autores principales: Bouard, Charlotte, Terreux, Raphael, Hope, Jennifer, Chemelle, Julie Anne, Puisieux, Alain, Ansieau, Stéphane, Payen, Léa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869052/
https://www.ncbi.nlm.nih.gov/pubmed/23527594
http://dx.doi.org/10.1080/07391102.2012.762722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869052/
https://www.ncbi.nlm.nih.gov/pubmed/23527594
http://dx.doi.org/10.1080/07391102.2012.762722

Ejemplares similares