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An automatic service for the personalization of ventricular cardiac meshes

Computational cardiac physiology has great potential to improve the management of cardiovascular diseases. One of the main bottlenecks in this field is the customization of the computational model to the anatomical and physiological status of the patient. We present a fully automatic service for the...

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Autores principales: Lamata, Pablo, Sinclair, Matthew, Kerfoot, Eric, Lee, Angela, Crozier, Andrew, Blazevic, Bojan, Land, Sander, Lewandowski, Adam J., Barber, David, Niederer, Steve, Smith, Nic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869175/
https://www.ncbi.nlm.nih.gov/pubmed/24335562
http://dx.doi.org/10.1098/rsif.2013.1023
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author Lamata, Pablo
Sinclair, Matthew
Kerfoot, Eric
Lee, Angela
Crozier, Andrew
Blazevic, Bojan
Land, Sander
Lewandowski, Adam J.
Barber, David
Niederer, Steve
Smith, Nic
author_facet Lamata, Pablo
Sinclair, Matthew
Kerfoot, Eric
Lee, Angela
Crozier, Andrew
Blazevic, Bojan
Land, Sander
Lewandowski, Adam J.
Barber, David
Niederer, Steve
Smith, Nic
author_sort Lamata, Pablo
collection PubMed
description Computational cardiac physiology has great potential to improve the management of cardiovascular diseases. One of the main bottlenecks in this field is the customization of the computational model to the anatomical and physiological status of the patient. We present a fully automatic service for the geometrical personalization of cardiac ventricular meshes with high-order interpolation from segmented images. The method is versatile (able to work with different species and disease conditions) and robust (fully automatic results fulfilling accuracy and quality requirements in 87% of 255 cases). Results also illustrate the capability to minimize the impact of segmentation errors, to overcome the sparse resolution of dynamic studies and to remove the sometimes unnecessary anatomical detail of papillary and trabecular structures. The smooth meshes produced can be used to simulate cardiac function, and in particular mechanics, or can be used as diagnostic descriptors of anatomical shape by cardiologists. This fully automatic service is deployed in a cloud infrastructure, and has been made available and accessible to the scientific community.
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spelling pubmed-38691752014-02-06 An automatic service for the personalization of ventricular cardiac meshes Lamata, Pablo Sinclair, Matthew Kerfoot, Eric Lee, Angela Crozier, Andrew Blazevic, Bojan Land, Sander Lewandowski, Adam J. Barber, David Niederer, Steve Smith, Nic J R Soc Interface Research Articles Computational cardiac physiology has great potential to improve the management of cardiovascular diseases. One of the main bottlenecks in this field is the customization of the computational model to the anatomical and physiological status of the patient. We present a fully automatic service for the geometrical personalization of cardiac ventricular meshes with high-order interpolation from segmented images. The method is versatile (able to work with different species and disease conditions) and robust (fully automatic results fulfilling accuracy and quality requirements in 87% of 255 cases). Results also illustrate the capability to minimize the impact of segmentation errors, to overcome the sparse resolution of dynamic studies and to remove the sometimes unnecessary anatomical detail of papillary and trabecular structures. The smooth meshes produced can be used to simulate cardiac function, and in particular mechanics, or can be used as diagnostic descriptors of anatomical shape by cardiologists. This fully automatic service is deployed in a cloud infrastructure, and has been made available and accessible to the scientific community. The Royal Society 2014-02-06 /pmc/articles/PMC3869175/ /pubmed/24335562 http://dx.doi.org/10.1098/rsif.2013.1023 Text en http://creativecommons.org/licenses/by/3.0/ © 2013 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Research Articles
Lamata, Pablo
Sinclair, Matthew
Kerfoot, Eric
Lee, Angela
Crozier, Andrew
Blazevic, Bojan
Land, Sander
Lewandowski, Adam J.
Barber, David
Niederer, Steve
Smith, Nic
An automatic service for the personalization of ventricular cardiac meshes
title An automatic service for the personalization of ventricular cardiac meshes
title_full An automatic service for the personalization of ventricular cardiac meshes
title_fullStr An automatic service for the personalization of ventricular cardiac meshes
title_full_unstemmed An automatic service for the personalization of ventricular cardiac meshes
title_short An automatic service for the personalization of ventricular cardiac meshes
title_sort automatic service for the personalization of ventricular cardiac meshes
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869175/
https://www.ncbi.nlm.nih.gov/pubmed/24335562
http://dx.doi.org/10.1098/rsif.2013.1023
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