Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent

An efficient method for the copper-catalyzed trifluoromethylation of terminal alkenes with an electrophilic trifluoromethylating reagent has been developed. The reactions proceeded smoothly to give trifluoromethylated alkenes in good to excellent yields. The results provided a versatile approach for...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Ping, Lin, Jin-Hong, Zhang, Cheng-Pan, Xiao, Ji-Chang, Zheng, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869243/
https://www.ncbi.nlm.nih.gov/pubmed/24367428
http://dx.doi.org/10.3762/bjoc.9.299
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author Wang, Xiao-Ping
Lin, Jin-Hong
Zhang, Cheng-Pan
Xiao, Ji-Chang
Zheng, Xing
author_facet Wang, Xiao-Ping
Lin, Jin-Hong
Zhang, Cheng-Pan
Xiao, Ji-Chang
Zheng, Xing
author_sort Wang, Xiao-Ping
collection PubMed
description An efficient method for the copper-catalyzed trifluoromethylation of terminal alkenes with an electrophilic trifluoromethylating reagent has been developed. The reactions proceeded smoothly to give trifluoromethylated alkenes in good to excellent yields. The results provided a versatile approach for the construction of C(vinyl)–CF(3) bonds without using prefunctionalized substrates.
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spelling pubmed-38692432013-12-23 Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent Wang, Xiao-Ping Lin, Jin-Hong Zhang, Cheng-Pan Xiao, Ji-Chang Zheng, Xing Beilstein J Org Chem Letter An efficient method for the copper-catalyzed trifluoromethylation of terminal alkenes with an electrophilic trifluoromethylating reagent has been developed. The reactions proceeded smoothly to give trifluoromethylated alkenes in good to excellent yields. The results provided a versatile approach for the construction of C(vinyl)–CF(3) bonds without using prefunctionalized substrates. Beilstein-Institut 2013-11-25 /pmc/articles/PMC3869243/ /pubmed/24367428 http://dx.doi.org/10.3762/bjoc.9.299 Text en Copyright © 2013, Wang et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Wang, Xiao-Ping
Lin, Jin-Hong
Zhang, Cheng-Pan
Xiao, Ji-Chang
Zheng, Xing
Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent
title Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent
title_full Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent
title_fullStr Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent
title_full_unstemmed Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent
title_short Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent
title_sort copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869243/
https://www.ncbi.nlm.nih.gov/pubmed/24367428
http://dx.doi.org/10.3762/bjoc.9.299
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