Cargando…

A one-pot synthesis of 3-trifluoromethyl-2-isoxazolines from trifluoromethyl aldoxime

Functionalized 3-trifluoromethyl-2-isoxazolines and 3-trifluoromethylisoxazoles were easily prepared from trifluoromethyl aldoxime 2 under mild conditions by using DIB as oxidant. Theoretical studies of the reactivity of trifluoroacetonitrile oxide 4 toward olefins and alkynes were carried out. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gonçalves, Raoni S B, Dos Santos, Michael, Bernadat, Guillaume, Bonnet-Delpon, Danièle, Crousse, Benoit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2013
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869255/ https://www.ncbi.nlm.nih.gov/pubmed/24367404 http://dx.doi.org/10.3762/bjoc.9.275

Ejemplares similares

Diastereoselective Additive Trifluoromethylation/Halogenation of Isoxazole Triflones: Synthesis of All-Carbon-Functionalized Trifluoromethyl Isoxazoline Triflones
por: Kawai, Hiroyuki, et al.
Publicado: (2014)

Synthesis of new triazole-based trifluoromethyl scaffolds
por: Martinelli, Michela, et al.
Publicado: (2008)

Product Control in Alkene Trifluoromethylation: Hydrotrifluoromethylation, Vinylic Trifluoromethylation, and Iodotrifluoromethylation using Togni Reagent
por: Egami, Hiromichi, et al.
Publicado: (2015)

Trifluoromethyl-substituted tetrathiafulvalenes
por: Jeannin, Olivier, et al.
Publicado: (2015)

Synthesis of trifluoromethylated 2H-azirines through Togni reagent-mediated trifluoromethylation followed by PhIO-mediated azirination
por: Sun, Jiyun, et al.
Publicado: (2018)

Cu and Hydroquinone for the Trifluoromethylation of Unprotected Phenols
por: Pletz, Jakob, et al.
Publicado: (2018)

Single enantiomer synthesis of α-(trifluoromethyl)-β-lactam
por: Jurčík, Václav, et al.
Publicado: (2011)

One-pot three-component route for the synthesis of S-trifluoromethyl dithiocarbamates using Togni’s reagent
por: Halimehjani, Azim Ziyaei, et al.
Publicado: (2017)

One pot synthesis of trifluoromethyl aryl sulfoxides by trifluoromethylthiolation of arenes and subsequent oxidation with hydrogen peroxide
por: Horvat, Monika, et al.
Publicado: (2020)

Difluoro-and Trifluoromethylation of Electron-Deficient Alkenes in an Electrochemical Microreactor
por: Arai, Kenta, et al.
Publicado: (2014)

Catalytic trifluoromethylation of iodoarenes by use of 2-trifluoromethylated benzimidazoline as trifluoromethylating reagent
por: Uchikura, Tatsuhiro, et al.
Publicado: (2020)

Highly Stable, Readily Reducible, Fluorescent, Trifluoromethylated 9‐Borafluorenes
por: Rauch, Florian, et al.
Publicado: (2020)

Polarity effects in 4-fluoro- and 4-(trifluoromethyl)prolines
por: Kubyshkin, Vladimir
Publicado: (2020)

Facile synthesis of 6-organyl-4-(trifluoromethyl)pyridin-2(1H)-ones and their polyfluoroalkyl-containing analogs
por: Kushch, S. O., et al.
Publicado: (2022)

Direct Stereoselective Aziridination of Cyclohexenols with 3‐Amino‐2‐(trifluoromethyl)quinazolin‐4(3H)‐one in the Synthesis of Cyclitol Aziridine Glycosidase Inhibitors
por: Artola, Marta, et al.
Publicado: (2019)

Electrophilic trifluoromethylselenolation of terminal alkynes with Se-(trifluoromethyl) 4-methylbenzenesulfonoselenoate
por: Ghiazza, Clément, et al.
Publicado: (2017)

Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent
por: Wang, Xiao-Ping, et al.
Publicado: (2013)

Synthesis, characterization and initial evaluation of 5-nitro-1-(trifluoromethyl)-3H-1λ(3),2-benziodaoxol-3-one
por: Santschi, Nico, et al.
Publicado: (2014)

Synthesis of trifluoromethyl ketones by nucleophilic trifluoromethylation of esters under a fluoroform/KHMDS/triglyme system
por: Fujihira, Yamato, et al.
Publicado: (2021)

β‐Octabromo‐ and β‐Octakis(trifluoromethyl)isocorroles: New Sterically Constrained Macrocyclic Ligands
por: Thomas, Kolle E., et al.
Publicado: (2017)

Acid catalyzed cyclodimerization of 2,2-bis(trifluoromethyl)-4-alkoxy-oxetanes and -thietanes. Synthesis of 2,2,6,6-tetrakis(trifluoromethyl)-4,8-dialkoxy-1,5-dioxocanes and 3,3,7,7-tetrakis(trifluoromethyl)-9-oxa-2,6-dithia-bicyclo[3.3.1]nonane
por: Petrov, Viacheslav A, et al.
Publicado: (2010)

Direct C–H trifluoromethylation of di- and trisubstituted alkenes by photoredox catalysis
por: Tomita, Ren, et al.
Publicado: (2014)

Cu-Mediated trifluoromethylation of benzyl, allyl and propargyl methanesulfonates with TMSCF(3)
por: Jiang, Xueliang, et al.
Publicado: (2013)

Palladium-catalyzed Heck-type reaction of secondary trifluoromethylated alkyl bromides
por: Fan, Tao, et al.
Publicado: (2017)

Synthesis of Trifluoromethylated Monoterpene Amino Alcohols
por: Petrova, Polina A., et al.
Publicado: (2022)

Synthesis of trifluoromethyl-substituted pyrazolo[4,3-c]pyridines – sequential versus multicomponent reaction approach
por: Palka, Barbara, et al.
Publicado: (2014)

Design and synthesis of novel poly (aryl ether ketones) containing trifluoromethyl and trifluoromethoxy groups
por: Liu, Xiaolong, et al.
Publicado: (2023)

Comparative profiling of well-defined copper reagents and precursors for the trifluoromethylation of aryl iodides
por: Kaplan, Peter T, et al.
Publicado: (2017)

Metal-free visible-light-enabled vicinal trifluoromethyl dithiolation of unactivated alkenes
por: Li, Xiaojuan, et al.
Publicado: (2021)

Regioselective Synthesis of 1-(2,6-Dichloro-4-Trifluoromethyl-phenyl)-4-Alkyl-1H-[1,2,3]-Triazoles
por: Hu, Huanan, et al.
Publicado: (2008)

Visible-light mediated carbonyl trifluoromethylative amination as a practical method for the synthesis of β-trifluoromethyl tertiary alkylamines
por: Kolahdouzan, Kavoos, et al.
Publicado: (2020)

Photoinduced Trifluoromethylation with CF(3)Br as a Trifluoromethyl Source: Synthesis of α-CF(3)-Substituted Ketones
por: Ma, Ransong, et al.
Publicado: (2022)

Trifluoromethyl ethers – synthesis and properties of an unusual substituent
por: Leroux, Frédéric R, et al.
Publicado: (2008)

Synthesis of Substituted α-Trifluoromethyl Piperidinic Derivatives
por: Rioton, Sarah, et al.
Publicado: (2017)

Catalytic Synthesis of Trifluoromethyl Cyclopropenes and Oligo‐Cyclopropenes
por: Tran, Uyen P. N., et al.
Publicado: (2020)

Enantioselective Copper-Catalyzed Synthesis of Trifluoromethyl-Cyclopropylboronates
por: Altarejos, Julia, et al.
Publicado: (2021)

Photophysical, photostability, and ROS generation properties of new trifluoromethylated quinoline-phenol Schiff bases
por: Rocha, Inaiá O, et al.
Publicado: (2021)

Ultrasound-assisted one-pot three-component synthesis of new isoxazolines bearing sulfonamides and their evaluation against hematological malignancies
por: Talha, Aicha, et al.
Publicado: (2021)

Synthesis of 5,10-bis(Trifluoromethyl) Substituted β-Octamethylporphyrins and Central-Metal-Dependent Solvolysis of Their meso-Trifluoromethyl Groups
por: Suzuki, Masaaki, et al.
Publicado: (2016)

Improved Synthesis of 2-Trifluoromethyl-10-aminopropylphenothiazine: Making 2-Trifluoromethyl-10-aminopropylphenothiazine Readily Available for Calmodulin Purification
por: Johnson, Josiah W., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4fhkrttil0dgp3uvef4iaf3dmm