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One-pot sequential synthesis of isocyanates and urea derivatives via a microwave-assisted Staudinger–aza-Wittig reaction

A fast and efficient protocol for the synthesis of N,N'-disubstituted urea derivatives from alkyl halides and primary or secondary amines has been developed. The synthetic pathway combines nucleophilic substitutions and a Staudinger–aza-Wittig reaction in the presence of polymer-bound diphenylp...

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Detalles Bibliográficos
Autores principales: Carnaroglio, Diego, Martina, Katia, Palmisano, Giovanni, Penoni, Andrea, Domini, Claudia, Cravotto, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869261/
https://www.ncbi.nlm.nih.gov/pubmed/24367403
http://dx.doi.org/10.3762/bjoc.9.274