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Towards stereochemical control: A short formal enantioselective total synthesis of pumiliotoxins 251D and 237A

A concise enantioselective synthesis of the advanced intermediate 5 for the synthesis of pumiliotoxins (Gallagher’s intermediate) is described. The synthesis started from the regio- and trans-diastereoselective (dr = 98:2) reductive 3-butenylation of (R)-3-(tert-butyldimethylsilyloxy)glutarimide 14....

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Detalles Bibliográficos
Autores principales:	Zhang, Jie, Zhang, Hong-Kui, Huang, Pei-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2013
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869269/ https://www.ncbi.nlm.nih.gov/pubmed/24367400 http://dx.doi.org/10.3762/bjoc.9.271

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