Synthesis of nucleotide–amino acid conjugates designed for photo-CIDNP experiments by a phosphotriester approach

Conjugates of 2’-deoxyguanosine, L-tryptophan and benzophenone designed to study pathways of fast radical reactions by the photo Chemically Induced Dynamic Nuclear Polarization (photo-CIDNP) method were obtained by the phosphotriester block liquid phase synthesis. The phosphotriester approach to the...

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Autores principales: Abramova, Tatyana V, Morozova, Olga B, Silnikov, Vladimir N, Yurkovskaya, Alexandra V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869286/
https://www.ncbi.nlm.nih.gov/pubmed/24367455
http://dx.doi.org/10.3762/bjoc.9.326
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author Abramova, Tatyana V
Morozova, Olga B
Silnikov, Vladimir N
Yurkovskaya, Alexandra V
author_facet Abramova, Tatyana V
Morozova, Olga B
Silnikov, Vladimir N
Yurkovskaya, Alexandra V
author_sort Abramova, Tatyana V
collection PubMed
description Conjugates of 2’-deoxyguanosine, L-tryptophan and benzophenone designed to study pathways of fast radical reactions by the photo Chemically Induced Dynamic Nuclear Polarization (photo-CIDNP) method were obtained by the phosphotriester block liquid phase synthesis. The phosphotriester approach to the oligonucleotide synthesis was shown to be a versatile and economic strategy for preparing the required amount of high quality samples of nucleotide–amino acid conjugates.
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spelling pubmed-38692862013-12-23 Synthesis of nucleotide–amino acid conjugates designed for photo-CIDNP experiments by a phosphotriester approach Abramova, Tatyana V Morozova, Olga B Silnikov, Vladimir N Yurkovskaya, Alexandra V Beilstein J Org Chem Full Research Paper Conjugates of 2’-deoxyguanosine, L-tryptophan and benzophenone designed to study pathways of fast radical reactions by the photo Chemically Induced Dynamic Nuclear Polarization (photo-CIDNP) method were obtained by the phosphotriester block liquid phase synthesis. The phosphotriester approach to the oligonucleotide synthesis was shown to be a versatile and economic strategy for preparing the required amount of high quality samples of nucleotide–amino acid conjugates. Beilstein-Institut 2013-12-18 /pmc/articles/PMC3869286/ /pubmed/24367455 http://dx.doi.org/10.3762/bjoc.9.326 Text en Copyright © 2013, Abramova et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Abramova, Tatyana V
Morozova, Olga B
Silnikov, Vladimir N
Yurkovskaya, Alexandra V
Synthesis of nucleotide–amino acid conjugates designed for photo-CIDNP experiments by a phosphotriester approach
title Synthesis of nucleotide–amino acid conjugates designed for photo-CIDNP experiments by a phosphotriester approach
title_full Synthesis of nucleotide–amino acid conjugates designed for photo-CIDNP experiments by a phosphotriester approach
title_fullStr Synthesis of nucleotide–amino acid conjugates designed for photo-CIDNP experiments by a phosphotriester approach
title_full_unstemmed Synthesis of nucleotide–amino acid conjugates designed for photo-CIDNP experiments by a phosphotriester approach
title_short Synthesis of nucleotide–amino acid conjugates designed for photo-CIDNP experiments by a phosphotriester approach
title_sort synthesis of nucleotide–amino acid conjugates designed for photo-cidnp experiments by a phosphotriester approach
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869286/
https://www.ncbi.nlm.nih.gov/pubmed/24367455
http://dx.doi.org/10.3762/bjoc.9.326
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