Rescue of behavioral and EEG deficits in male and female Mecp2-deficient mice by delayed Mecp2 gene reactivation

Mutations of the X-linked gene encoding methyl CpG binding protein type 2 (MECP2) are the predominant cause of Rett syndrome, a severe neurodevelopmental condition that affects primarily females. Previous studies have shown that major phenotypic deficits arising from MeCP2-deficiency may be reversib...

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Detalles Bibliográficos
Autores principales: Lang, Min, Wither, Robert G., Colic, Sinisa, Wu, Chiping, Monnier, Philippe P., Bardakjian, Berj L., Zhang, Liang, Eubanks, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869352/
https://www.ncbi.nlm.nih.gov/pubmed/24009314
http://dx.doi.org/10.1093/hmg/ddt421

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