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Minimally invasive transplantation of iPSC-derived ALDHhiSSCloVLA4+ neural stem cells effectively improves the phenotype of an amyotrophic lateral sclerosis model
Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease characterized by the degeneration of motor neurons. Currently, there is no effective therapy for ALS. Stem cell transplantation is a potential therapeutic strategy for ALS, and the reprogramming of adult somatic cells into induced p...
Autores principales: | Nizzardo, Monica, Simone, Chiara, Rizzo, Federica, Ruggieri, Margherita, Salani, Sabrina, Riboldi, Giulietta, Faravelli, Irene, Zanetta, Chiara, Bresolin, Nereo, Comi, Giacomo P., Corti, Stefania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869354/ https://www.ncbi.nlm.nih.gov/pubmed/24006477 http://dx.doi.org/10.1093/hmg/ddt425 |
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