Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles

Gold(I) complexes have emerged as powerful and useful catalysts for the formation of new C–C, C–O and C–N bonds. Taking advantage of the specificity of [IPrAuNCMe][SbF(6)] complexes to favor the 5-exo-dig cyclization over the 6-endo-dig pathway, we report a high yielding and efficient method to gene...

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Detalles Bibliográficos
Autores principales: Morin, Mathieu, Levesque, Patrick, Barriault, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869369/
https://www.ncbi.nlm.nih.gov/pubmed/24367426
http://dx.doi.org/10.3762/bjoc.9.297
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author Morin, Mathieu
Levesque, Patrick
Barriault, Louis
author_facet Morin, Mathieu
Levesque, Patrick
Barriault, Louis
author_sort Morin, Mathieu
collection PubMed
description Gold(I) complexes have emerged as powerful and useful catalysts for the formation of new C–C, C–O and C–N bonds. Taking advantage of the specificity of [IPrAuNCMe][SbF(6)] complexes to favor the 5-exo-dig cyclization over the 6-endo-dig pathway, we report a high yielding and efficient method to generate substituted polyaromatic heterocycles under remarkably mild reaction conditions.
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spelling pubmed-38693692013-12-23 Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles Morin, Mathieu Levesque, Patrick Barriault, Louis Beilstein J Org Chem Full Research Paper Gold(I) complexes have emerged as powerful and useful catalysts for the formation of new C–C, C–O and C–N bonds. Taking advantage of the specificity of [IPrAuNCMe][SbF(6)] complexes to favor the 5-exo-dig cyclization over the 6-endo-dig pathway, we report a high yielding and efficient method to generate substituted polyaromatic heterocycles under remarkably mild reaction conditions. Beilstein-Institut 2013-11-22 /pmc/articles/PMC3869369/ /pubmed/24367426 http://dx.doi.org/10.3762/bjoc.9.297 Text en Copyright © 2013, Morin et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Morin, Mathieu
Levesque, Patrick
Barriault, Louis
Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles
title Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles
title_full Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles
title_fullStr Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles
title_full_unstemmed Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles
title_short Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles
title_sort gold(i)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869369/
https://www.ncbi.nlm.nih.gov/pubmed/24367426
http://dx.doi.org/10.3762/bjoc.9.297
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