Cargando…
Review: The history and role of naturally occurring mouse models with Pde6b mutations
Mouse models are useful tools for developing potential therapies for human inherited retinal diseases, such as retinitis pigmentosa (RP), since more strains are being identified with the same mutant genes and phenotypes as humans with corresponding retinal degenerative diseases. Mutations in the bet...
Autores principales: | Han, Juanjuan, Dinculescu, Astra, Dai, Xufeng, Du, Wei, Smith, W. Clay, Pang, Jijing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869645/ https://www.ncbi.nlm.nih.gov/pubmed/24367157 |
Ejemplares similares
-
Cone Phosphodiesterase-6γ’ Subunit Augments Cone PDE6 Holoenzyme Assembly and Stability in a Mouse Model Lacking Both Rod and Cone PDE6 Catalytic Subunits
por: Deng, Wen-Tao, et al.
Publicado: (2018) -
Gene Therapy in a Large Animal Model of PDE6A-Retinitis Pigmentosa
por: Mowat, Freya M., et al.
Publicado: (2017) -
Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential
por: Li, Qiuhong, et al.
Publicado: (2008) -
A Modified Arrestin1 Increases Lactate Production in the Retina and Slows Retinal Degeneration
por: Nelson, Tiffany S., et al.
Publicado: (2022) -
Novel variants in PDE6A and PDE6B genes and its phenotypes in patients with retinitis pigmentosa in Chinese families
por: Li, Yuyu, et al.
Publicado: (2022)