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Inferring Short-Range Linkage Information from Sequencing Chromatograms

Direct Sanger sequencing of viral genome populations yields multiple ambiguous sequence positions. It is not straightforward to derive linkage information from sequencing chromatograms, which in turn hampers the correct interpretation of the sequence data. We present a method for determining the var...

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Detalles Bibliográficos
Autores principales: Beggel, Bastian, Neumann-Fraune, Maria, Kaiser, Rolf, Verheyen, Jens, Lengauer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869653/
https://www.ncbi.nlm.nih.gov/pubmed/24376502
http://dx.doi.org/10.1371/journal.pone.0081687