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Generalized Baum-Welch Algorithm Based on the Similarity between Sequences
The profile hidden Markov model (PHMM) is widely used to assign the protein sequences to their respective families. A major limitation of a PHMM is the assumption that given states the observations (amino acids) are independent. To overcome this limitation, the dependency between amino acids in a mu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869655/ https://www.ncbi.nlm.nih.gov/pubmed/24376498 http://dx.doi.org/10.1371/journal.pone.0080565 |