Predictive Efficacy of Low Burden EGFR Mutation Detected by Next-Generation Sequencing on Response to EGFR Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Carcinoma

Direct sequencing remains the most widely used method for the detection of epidermal growth factor receptor (EGFR) mutations in lung cancer; however, its relatively low sensitivity limits its clinical use. The objective of this study was to investigate the sensitivity of detecting an epidermal growt...

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Detalles Bibliográficos
Autores principales: Kim, Hye Sook, Sung, Jae Sook, Yang, Song-Ju, Kwon, Nak-Jung, Jin, LiHua, Kim, Seung Tae, Park, Kyong Hwa, Shin, Sang Won, Kim, Han Kyeom, Kang, Jin-Hyoung, Kim, Jeong-Oh, Park, Jae Yong, Choi, Jin Eun, Yoon, HyoungKyu, Park, Chan Kwon, Yang, Kap-Seok, Seo, Jeong-Sun, Kim, Yeul Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869671/
https://www.ncbi.nlm.nih.gov/pubmed/24376508
http://dx.doi.org/10.1371/journal.pone.0081975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869671/
https://www.ncbi.nlm.nih.gov/pubmed/24376508
http://dx.doi.org/10.1371/journal.pone.0081975

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