Cargando…
Prestin Regulation and Function in Residual Outer Hair Cells after Noise-Induced Hearing Loss
The outer hair cell (OHC) motor protein prestin is necessary for electromotility, which drives cochlear amplification and produces exquisitely sharp frequency tuning. Tecta(C1509G) transgenic mice have hearing loss, and surprisingly have increased OHC prestin levels. We hypothesized, therefore, that...
Autores principales: | Xia, Anping, Song, Yohan, Wang, Rosalie, Gao, Simon S., Clifton, Will, Raphael, Patrick, Chao, Sung-il, Pereira, Fred A., Groves, Andrew K., Oghalai, John S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869702/ https://www.ncbi.nlm.nih.gov/pubmed/24376553 http://dx.doi.org/10.1371/journal.pone.0082602 |
Ejemplares similares
-
Spatiotemporal Developmental Upregulation of Prestin Correlates With the Severity and Location of Cyclodextrin-Induced Outer Hair Cell Loss and Hearing Loss
por: Ding, Dalian, et al.
Publicado: (2021) -
Prestin-Dependence of Outer Hair Cell Survival and Partial Rescue of Outer Hair Cell Loss in Prestin
(V499G/Y501H) Knockin Mice
por: Cheatham, Mary Ann, et al.
Publicado: (2015) -
A666-conjugated nanoparticles target prestin of outer hair cells preventing cisplatin-induced hearing loss
por: Wang, Xueling, et al.
Publicado: (2018) -
High frequency of the IVS2-2A>G DNA sequence variation in SLC26A5, encoding the cochlear motor protein prestin, precludes its involvement in hereditary hearing loss
por: Tang, Hsiao-Yuan, et al.
Publicado: (2005) -
Elevator-like movements of prestin mediate outer hair cell electromotility
por: Kuwabara, Makoto F., et al.
Publicado: (2023)