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Inhibition of Human Neutrophil Elastase by Pentacyclic Triterpenes

SCOPE: Inhibiting human neutrophil elastase (HNE) is a promising strategy for treating inflammatory lung diseases, such as H1N1 and SARS virus infections. The use of sivelestat, the only clinically registered synthesized HNE inhibitor, is largely limited by its risk of organ toxicity because it irre...

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Detalles Bibliográficos
Autores principales:	Feng, Li, Liu, Xiaoyu, Zhu, Weiliang, Guo, Fujiang, YingchunWu, Wang, Rui, Chen, Kaixian, Huang, Cheng, Li, Yiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869726/ https://www.ncbi.nlm.nih.gov/pubmed/24376583 http://dx.doi.org/10.1371/journal.pone.0082794

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