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MicroRNA-10b Promotes Nucleus Pulposus Cell Proliferation through RhoC-Akt Pathway by Targeting HOXD10 in Intervetebral Disc Degeneration
Aberrant proliferation of nucleus pulposus cell is implicated in the pathogenesis of intervertebral disc degeneration. Recent findings revealed that microRNAs, a class of small noncoding RNAs, could regulate cell proliferation in many pathological conditions. Here, we showed that miR-10b was dramati...
Autores principales: | Yu, Xin, Li, Zheng, Shen, Jianxiong, Wu, William K. K., Liang, Jinqian, Weng, Xisheng, Qiu, Guixing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869743/ https://www.ncbi.nlm.nih.gov/pubmed/24376640 http://dx.doi.org/10.1371/journal.pone.0083080 |
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