Use of Net Reclassification Improvement (NRI) Method Confirms The Utility of Combined Genetic Risk Score to Predict Type 2 Diabetes

BACKGROUND: Recent genome-wide association studies (GWAS) identified more than 70 novel loci for type 2 diabetes (T2D), some of which have been widely replicated in Asian populations. In this study, we investigated their individual and combined effects on T2D in a Chinese population. METHODOLOGY: We...

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Detalles Bibliográficos
Autores principales: Tam, Claudia H. T., Ho, Janice S. K., Wang, Ying, Lam, Vincent K. L., Lee, Heung Man, Jiang, Guozhi, Lau, Eric S. H., Kong, Alice P. S., Fan, Xiaodan, Woo, Jean L. F., Tsui, Stephen K. W., Ng, Maggie C. Y., So, Wing Yee, Chan, Juliana C. N., Ma, Ronald C. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869744/
https://www.ncbi.nlm.nih.gov/pubmed/24376643
http://dx.doi.org/10.1371/journal.pone.0083093

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